Calcipotriol/Calcipotriene+Betamethasone, Dovobet (CDN)/Enstilar/Taclonex (US)
Description: Topical Vitamin D Analog; Topical Corticosteroid
CSA NA – FDA Approved – REMS (N) – Can Ship
How Does It Work
Calcipotriol/Calcipotriene is a synthetic vitamin D3 analog that regulates skin cell production and proliferation. It activates vitamin D receptors and inhibits the proliferation of keratinocytes and enhances their differentiation.
Betamethasone may reduce the formation, release, and activity of inflammatory mediators such as kinins, histamine and prostaglandins. Reduces cell migration to the affected area and reverses the dilation and blood vessel permeability result in decreased access of cells to the site. It has anti-inflammatory, vasoconstrictive, and antipruritic properties.
Indications For Use
Calcipotriol/Calcipotriene+Betamethasone, Dovobet/Enstilar/Taclonex is indicated for plaque psoriasis.
Before starting the use of Calcipotriol/Calcipotriene+Betamethasone, Dovobet/Enstilar/Taclonex make sure your physician is aware of any allergies or medications you currently take, if you have any active skin conditions/infections, or if you are pregnant or breastfeeding. May cause hypercalcemia if it occurs hold medication until it resolves.
Apply to the affected area(s) once daily as prescribed
Pharmacist Tips On Using
How to Take: Follow instructions provided by physician/pharmacy label, apply consistently at same times each day unless otherwise directed, store at room temperature. Apply to affected skin; rub in gently and completely. Wash hands thoroughly after use.
You Need to Avoid: Avoid application to broken or infected skin unless directed by a physician. Avoid applying other topicals at the same time unless otherwise directed to avoid dilution of the product. Not to be applied to groin, axillae, face, or diaper area. Avoid application to broken or infected skin unless directed by a physician.
Burning, stinging, rash and itching of the application site, HPA axis suppression
Note this is not a complete list of side effects