Acne, Topical Skin Product
CSA NA – FDA Approved – REMS (N) – Can Ship
How Does It Work
Adapalene is a retinoid-like compound that acts as a modulator of cell differentiation, keratinization, and inflammatory processes, all of which represent important features in the pathology of acne vulgaris.
Indications For Use
Officially indicated to treat acne vulgaris.
Do not use in patients with hypersensitivity to tretinoin or any component of the formulation.
Watch for signs of an allergic reaction which can include: rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing or talking; or swelling of the mouth, face, lips, tongue or throat.
Risk of photosensitivity and skin irritation
Topical: Apply once daily in the evening before bedtime. If irritation occurs, may reduce the frequency of application.
Pharmacist Tips On Using
How to Use Adapalene, Differin: Apply adapalene/Differin as directed by your doctor and use only on your skin; keep it out of your mouth, nose, and eyes. Do not apply on any mucous membranes. Avoid using occlusive dressing or wrappings. For cream/gel apply a thin layer to clean, dry skin before bedtime. For lotion apply after washing the area with a mild or soapless cleanser and dry. Apply about 3 to 4 pump actuation to cover the entire face.
Some Common Side Effects When Using Adapalene, Differin: Skin irritation such as itchiness, burning, or stinging may occur, this generally occurs during the first few weeks of therapy. If a severe skin irritation or sensitivity reaction occurs discontinue use. Adapalene/Differin can make the skin more susceptible/sensitive to UV light, increasing the risk of getting a sunburn. Make sure to use sunscreen daily and other protective measures.
The most common side effects occur on at the site of skin application. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
Dermatologic: Xeroderma (≤45%), exfoliation of skin (≤44%), erythema (≤38%), burning sensation of skin (≤29%), stinging of the skin (≤29%)