Description: Antifungal Agent, Echinocandin
CSA NA – FDA Approved – REMS (N) – Can Ship
How Does It Work
Inhibits synthesis of β(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. The highest activity is in regions of active cell growth. Mammalian cells do not require β(1,3)-D-glucan, limiting potential toxicity.
Indications For Use
Aspergillosis, Candidemia and other Candida Infections
Before starting Caspofungin, Cancidas make sure your physician is aware of any allergies or medications you currently take. Taking Caspofungin, Cancidas comes with a higher risk of experiencing hepatic effects (i.e. hepatic failure, hepatitis).
Intravenous: Initial dose of 70mg on day 1; subsequent dosing at 50 mg once daily; generally continue for at least 14 days after the last positive culture or longer if neutropenia warrants.
Pharmacist Tips On Using
Intravenous: Infuse slowly over ~1 hour. Do not administer IV bolus.
Hypotension, peripheral edema, chills, headache, skin rash, diarrhea, nausea, hematologic effects (i.e. decrease in hematocrit, hemoglobin, white blood cells), elevated liver enzymes, phlebitis, respiratory failure, cough, infusion-related reactions, fever, and septic shock.
Note this is not a complete list of side effects for Caspofungin, Cancidas only common ones.
Frequently Asked Questions
What do I do if side effects are intolerable?
If the symptoms are causing a lot of distress speak to your physician as soon as possible to discuss how to manage the side effects or to consider therapy modification.