Ophthalmic Alpha2 Agonist; Ophthalmic Carbonic Anhydrase Inhibitor
CSA NA – FDA Approved – REMS (N) – Can Ship
How Does it Work
Brinzolamide inhibits carbonic anhydrase which reduces the secretion of aqueous humor, thereby reducing intraocular pressure.
Brimonidine reduces aqueous humor production and increases uveoscleral outflow via selective alpha2 agonism thereby reducing intraocular pressure.
Indications For Use
Brinzolamide + Brimonidine (Ophthalmic), Simbrinza is officially indicated to treat elevated intraocular pressure secondary to open angle glaucoma or ocular hypertension.
Before starting Brinzolamide+Brimonidine (Ophthalmic), Simbrinza makes sure your physician is aware of any allergies (Sulfa) or medications you currently take if you have liver disease, kidney disease, acute angle closure glaucoma, cardiovascular disease, cerebrovascular insufficiency, if you are pregnant, or breastfeeding.
Instill one drop into the affected eye(s) every 8 hours.
Pharmacist Tips On Using
How to Take Brinzolamide+Brimonidine (Ophthalmic), Simbrinza: Follow instructions provided by physician/pharmacy label, use consistently at same times each day unless otherwise directed, store at room temperature. Shake the suspension before use and apply light pressure to lacrimal sac (inside corner of the eye near nose) for 60 seconds after application to prevent drainage of the drop from the eye
You Need to Avoid: Remove contact lenses before applying and wait at least 15 minutes after administration before reinserting.
Local irritation, blurred vision, dysgeusia (altered taste), xerostomia (dry mouth).
Note this is not a complete list of side effects, just the most common ones.
Frequently Asked Questions
What do I do if I am prescribed multiple eyedrops at the same time?
If they are to be administered at the same time, wait at least 10 minutes between each kind of drop to allow time for the medication to absorb into the eye. Applying two different drops too close to each other will cause dilution of each resulting in a reduced effect of both. given to allow to soak in. This is commonly done as there are many commercially available eye drops and only a few kinds of eardrop.