Antidiabetic Agent, Dipeptidyl Peptidase 4 (DPP-4) Inhibitor
CSA NA – FDA Approved – REMS (N) – Can Ship
How Does It Work
Alogliptin, Nesina is a dipeptidyl peptidase 4 (DPP-4) inhibitor that results an increase in incretin levels. Incretin hormones (eg, glucagon-like peptide-1 [GLP-1] and glucose-dependent insulinotropic polypeptide [GIP]) regulate glucose homeostasis by increasing insulin synthesis and release from pancreatic beta cells and decreasing glucagon secretion from pancreatic alpha cells. Decreased glucagon secretion results in decreased hepatic glucose production.
Indications For Use
Diabetes Mellitus, Type 2
Before starting Alogliptin, Nesina make sure your physician is aware of any allergies or medications you currently take. Alogliptin, Nesina have been shown to cause disabling arthralgia, bullous pemphigoid, hepatotoxicity, pancreatitis. Alogliptin, Nesina should be used with caution in patients with heart failure, renal and hepatic impairment because of the risk to worsening their pre-existing condition.
Oral: 25mg daily.
Pharmacist Tips On Using
How to Take: Can take with or without food.
Headache, renal function abnormality, nasopharyngitis, upper respiratory tract infection.
Note this is not a complete list of side effects for Alogliptin, Nesina only common ones
Frequently Asked Questions
What do I do if side effects are intolerable?
If side effects are causing a lot of distress speak to your physician as soon as possible to discuss options.