Nadolol, Corgard
Description: Antianginal Agent; Antihypertensive; Beta-Blocker, Nonselective
“Alert: Black Box Warning
Exacerbation of ischemic heart disease following abrupt withdrawal:
Hypersensitivity to catecholamines has been observed in patients withdrawn from beta-blocker therapy; exacerbation of angina and, in some cases, myocardial infarction have occurred after abrupt discontinuation of such therapy. When discontinuing nadolol administered long term, particularly in patients with ischemic heart disease, gradually reduce the dosage over a period of 1 to 2 weeks and carefully monitor the patient. If angina markedly worsens or acute coronary insufficiency develops, reinstitute nadolol administration promptly, at least temporarily, and take other measures appropriate for the management of unstable angina. Warn patients against interruption or discontinuation of therapy without the health care provider’s advice. Because coronary artery disease is common and may be unrecognized, it may be prudent not to discontinue nadolol therapy abruptly, even in patients treated only for hypertension.”
CSA NA – FDA Approved – REMS (N) – Can Ship
How Does It Work
Nadolol, Corgard is a non-selective beta blocker that blocks both beta1– and beta2-adrenergic stimulation mainly around the heart causing a decrease in heart rate and blood pressure.
Indications For Use
Angina, hypertension
Precautions
Before starting Nadolol, Corgard make sure your physician is aware of any allergies or medications you currently take. Nadolol, Corgard should be used with caution if you have bronchospastic disease, conduction abnormalities, diabetes, heart failure, renal impairment, and thyroid disease because of its capacity to exacerbate symptoms.
Usual Dosing
Oral: 40mg to 320mg daily.
Pharmacist Tips On Using
How to Take: Can be taken with or without food.
Side Effects
Drowsiness, insomnia, bradycardia, cardiac failure, edema, hypotension, depression, dizziness, fatigue.
Note this is not a complete list of side effects for Nadolol, Corgard only common ones
Frequently Asked Questions
Why am I so tired since starting Nadolol, Corgard?
It is a common side effect that is not harmful and after 2 weeks or so it should subside as it adjusts to the medication. It is important to try and give the medication at least 2 weeks if fatigue is an issue as it usually will resolve. If side effects are intolerable speak to your physician, do not discontinue medication without their consent as this can be a vital medication to take for many conditions.
Why does exercise exhaust me so much more since starting this medication?
Blocking cardiac output can lower your exercise tolerance as the heart cannot pump as hard or fast as it used to in response to exercise. This is normal and helps protect the heart from overworking itself in many cardiac conditions.