Azelastine Hydrochloride+Fluticasone Propionate (Nasal), Dymista
Description: Corticosteroid, Antihistamine
CSA NA – FDA Approved – REMS (N) – Can Ship
How Does It Work
Dymista is a nasal spray that combines Azelastine, an antihistamine and fluticasone propionate, a corticosteroid. Azelastine acts on the immediate allergic phase reducing allergic rhinitis symptoms such as a runny nose and nasal itchiness. Azelastine blocks histamine H1 receptor sites on effector cells and subsequently inhibits the release of histamine and other mediators involved in the allergic response. Fluticasone is a corticosteroid that acts as a potent vasoconstrictor and anti-inflammatory.
Indications For Use
Seasonal allergic rhinitis
Before starting Azelastine Hydrochloride+Fluticasone Propionate, Dymista makes sure your physician is aware of any allergies or medications you currently take, and activities you perform. Fluticasone propionate may cause hypercortisolism or suppression of the hypothalamic-pituitary-adrenal (HPA) axis, particularly in children or when used over a prolonged period of time. Prolonged use of fluticasone propionate can also increase the incidence of secondary infection, mask acute infection and/or prolong or exacerbate an existing infection. Avoid using Azelastine Hydrochloride+Fluticasone Propionate, Dymista in patients with nasal septal ulcers, nasal surgery or nasal trauma until complete healing has occurred.
Azelastine Hydrochloride+Fluticasone Propionate, Dymista should be used with caution in patients with ocular herpes simplex, latent tuberculosis, untreated infections (viral, fungal, bacterial, parasitic) and ocular diseases such as glaucoma and/or cataracts.
Usual (Nasal): use one spray in each nostril twice daily.
Pharmacist Tips On Using
How to Use: Prime the nasal spray prior to first use by pressing the pump 6 times. If ≥14 days have elapsed since last use, then reprime pump with 1 spray or until a fine mist appears. Shake the bottle gently before using. Blow nose to clear nostrils. Keep head tilted downward when spraying. Insert applicator tip 1/4 to 1/2 inch into the nostril, keeping the bottle upright, and close off the other nostril. Breathe in through the nose. While inhaling, press the pump to release spray. After each use, wipe the spray tip with a clean tissue or cloth and replace the cap. Clean spray pump unit and dust cap at least 1 time each week in warm water and allow to completely dry before placing back on the bottle. Avoid spraying directly into nasal septum, eyes or mouth.
Headache, dysgeusia, epistaxis
Note this is not a complete list of side effects, only the most common.
Frequently Asked Questions
What do I do if the side effects are not tolerable?
If the side effects are causing a lot of distress speak to our physician as soon as possible to discuss options.