Aclidinium+Formoterol, Duaklir Pressair (US)/Duaklir Genuair (Canada)
Description: Anticholinergic, Beta agonist, long-acting, inhalant (oral)
Brand Name US: Duaklir Pressair
Canadian Equivalent: Dualir Genuair
CSA NA – FDA Approved – REMS (N) – Can Ship
How Does It Work
Aclidinium is an anticholinergic agent that is a reversible competitive inhibitor of type 3 muscarinic (M3) receptors which cause the smooth muscle in the bronchi to relax and subsequently lead to bronchodilation.
Formoterol is a selective beta-agonist that binds to beta2 receptors located on the bronchial smooth muscle causing the airway to dilate reducing the work required to breathe while having little effect on heart rate.
Indications For Use
Chronic obstructive pulmonary disease
Before starting Aclidinium+Formoterol, Duaklir Pressair/Duaklir Genuair make sure your physician is aware of any allergies or medications you currently take. Hyperthyroidism, cardiovascular disease, electrolyte disturbances, urinary retention, and rare paradoxical cases of life-threatening bronchospasm have been reported.
Oral Inhalation: Dry Powder inhaler
Take one inhalation twice daily.
Pharmacist Tips On Using
How to Take Aclidinium+Formoterol, Duaklir Pressair/Duaklir Genuair
The inhaler is breath actuated; administer via oral inhalation once in the morning and evening. Remove the inhaler from the sealed bag immediately prior to first use. To load the dose, remove the protective cap and press the orange button all the way down (avoid tilting the inhaler). If the control window is green, the inhaler is ready for use; if the control window is red, reactivate the inhaler again by pressing and releasing the orange button. Prior to inhaling the dose, exhale fully (do not exhale into the inhaler), then close lips tightly around the inhaler mouthpiece and inhale (rapidly, steadily, and deeply); do not hold the orange button down while inhaling. Keep breathing in even after a “click” is heard to ensure that the full dose has been given. Ensure the dose was delivered correctly by observing the control window change from green to red; if the control window is still green, repeat inhalation steps. When the control window has been verified as red, replace the protective cap until next use. Do not wash or put inhaler in water; mouthpiece may be cleaned with a dry tissue or cloth. Discard the inhaler when the dose counter displays “0” or within 60 days after removal from the sealed bag (whichever occurs first). Refer to the product labeling for additional administration instructions.
Headache, dizziness, insomnia, urinary tract infection, muscle and joint pain, cough, and sinusitis.
Note this is not a complete list of side effects for Aclidinium+Formoterol, Duaklir Pressair/Duaklir Genuair, only common ones.
Frequently Asked Questions
Why is my heart racing/ am I stimulated after using Aclidinium+Formoterol, Duaklir Pressair/Duaklir Genuair?
Formoterol works on specific adrenaline receptors however it sometimes will activate other adrenaline receptors that results in increased heart rate/ mental stimulation
Why does one brand of inhaler feel differently than another?
Different brands of metered-dose inhalers may use different propelling agents and dry powder inhalers have such a small amount of powder dispensed you likely will not feel it