Clindamycin/Benzoyl Peroxide (Topical), BenzaClin/Clindoxyl
Description: Topical Acne Product; Topical Antibiotic
CSA NA – FDA Approved – REMS (N) – Can Ship
How Does It Work
Clindamycin binds to ribosomal 50S subunits of certain bacteria thereby stopping protein synthesis for the cell eventually resulting in cell death. Maybe bacteriostatic (prevents reproduction) or bactericidal (directly kills live bacteria) depending on the dosage.
Benzoyl Peroxide releases free radical oxygen which oxidizes bacterial proteins in the sebaceous follicles which kills anaerobic bacteria and decreasing irritating-type free fatty acids.
Indications For Use
Clindamycin+Benzoyl Peroxide/BenzaClin/Clindoxyl is officially indicated for acne vulgaris and is sometimes prescribed off-label for acne rosacea.
Precautions
Before starting the use of Clindamycin+Benzoyl Peroxide/BenzaClin/Clindoxyl make sure your physician is aware of any allergies or medications you currently take, or if you are pregnant or breastfeeding.
Usual Dosing
Apply to the affected area(s) once or twice daily
Pharmacist Tips On Using
How to Take: Follow instructions provided by physician/pharmacy label, apply consistently at same times each day unless otherwise directed, apply to clean, dry skin, store at room temperature.
You Need to Avoid: Do not apply near eyes, to broken skin, or to other mucous membranes. Avoid applying other topicals at the same time unless otherwise directed to avoid dilution of the product. Benzoyl peroxide may cause bleaching of hair or fabrics such as on pillowcases when applied to the face before bed.
Side Effects
Application site scaling, local dryness, erythema (redness), desquamation (peeling), itch
Note this is not a complete list of side effects, only common ones